HORDB

ID: hor004183
Uniprot ID: B7X9Y6
Protein name: Angiotensin I
Gene name: agt
Organism: Triakis scyllium (Banded houndshark) (Hemigaleus pingi)
Family: Serpin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Triakis (genus), Triakidae (family), Carcharhiniformes (order), Galeoidea (superorder), Galeomorphii, Selachii (infraclass), Elasmobranchii (subclass), Chondrichthyes (class), Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0004867 serine-type endopeptidase inhibitor activity
GO BP: NA
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space

Sequence: NRPYIHPFQL
Length: 10(20-29)
Propeptide: MRWIFSLLWVGALLEWGTTNRPYIHPFQLFTCNRTEFQEEMDRNNSFLPEQSPVNMSEEWWENELWKVSPTKMFTLISLQMSLAKIWFAKLGSLEESGVTLLSPVHLYESLAALSLGAGGATAKSFREHLGLMDYRCVGDRHSWVMRWQGRLLHHDILTRQEGSVSTGAWLIFRKGLQLRRAFSWELRWFYPQVQLRAADCNQPRVAEETINSLVLNATGGRVSNLVTGLSPSTNLVLASYIHFTGKWQSRSQCQ
Signal peptide: MRWIFSLLWVGALLEWGTT
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004183_AF2.pdb

hor004183_ESM.pdb

Mass:	144519	Formula:	C61H89N17O14
Absent amino acids:	ACDEGKMSTVW	Common amino acids:	P
pI:	9.35	Basic residues:	2
Polar residues:	2	Hydrophobic residues:	3
Hydrophobicity:	-81	Boman Index:	-1908
Half-Life:	1.4 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	78
Instability Index:	5698	Extinction Coefficient cystines:	1490
Absorbance 280nm:	165.56